I don’t want to die, but apparently Daniel Callahan wants me to. He wants me to say nothing, do nothing about aging and just wait until I am 75 and die quietly. Well, that’s not going to happen, mister. Bioethicisits like Callahan are the ones responsible for our suffering from the horrors of aging-related diseases and death. And here’s why. The opinion of bioethicists prevents the progress from being fast enough to cure aging. The decision-makers rely upon what senior “thinkers” like Callahan have in mind on the problem of life extension.
The study, conducted by a team of scientists and clinicians from JCVI and WCHN, will focus on two groups of elderly individuals aged 65 to 85 years by correlating genetics with a variety of human genomic, gut microbiome and other “omics” profiles and integrating these data with the individuals’ health record. One group will consist of healthy individuals, and the other will have individuals with a variety of diagnosed health conditions.
On September 18 Google announced their crusade against death via the Time journal cover. Calico company was created specifically to fight aging. Larry page made it clear for the shareholders that Google is an innovative company and that they can afford the most courageous projects, while the investments won’t be too large and won’t undermine the foundations of the company.
My friend Michelle has done something very important and very useful to all of us – she donated money to aging research. I believe this is how we can change the situation – by following Michelle’s example.
I’ve heard you are interested in the topics of aging and longevity. This is very cool, because fighting for radical life extension is the wisest and most humanitarian strategy. I would like to tell you what needs to be done, but, unfortunately, I haven’t got your email address, or any other way to be heard.
Artificial Intelligence is a set of tools that are driving forward key parts of the futurist agenda, sometimes at a rapid clip. The last few years have seen a slew of surprising advances: the IBM supercomputer Watson, which beat two champions of Jeopardy!; self-driving cars that have logged over 300,000 accident-free miles and are officially legal in three states; and statistical learning techniques are conducting pattern recognition on complex data sets from consumer interests to trillions of images. In this post, I’ll bring you up to speed on what is happening in AI today, and talk about potential future applications.
Did you know that there are only 138 mutations that play the major role in making a cell cancerous? Well, 138 found so far, however, the number of these driver mutations inside the genes won’t grow significantly, at least that’s not anticipated. Obviously there are thousands of mutations in cancer cells, but not all of them give the selective grow advantage.
Knowing what kind of genes are involved in the main biological processes is much more relevant to your life than which car is faster, Porsche or Jaguar. And I’m not talking about dangerous driving here. I am talking about the crucial information about the genes that govern your longevity. You have to know what they are, what they do, what happens to them during aging and what are the ways to make them work better, towards keeping you young for a longer time. I am reprinting the text of the article written by Dr. Matthew Carter and Dr. Anne Brunet from Stanford University. I let myself explain some of the biological terms in brackets to make this beautifully written story of one gene a bit simpler. This is a must-read.
Arthur Caplan, renowned bioethicist, presents simply brilliant argumentation that aging is an unnatural process in this paper. It’s a must-read. I’d love to highlight the main thoughts that I find are profoundly important for the whole fighting aging field.
The recent Nature journal special edition is dedicated completely to the problem of aging. Among various articles covering topics from demographics to comparative biology and robots, there’s one about the interventions in the aging processes. It is a nice overview about the current successes in slowing down aging in mammals, however I found the last paragraph rather disappointing. It says….
I have just got back from Oman, one of the most progressive countries in the Middle East with their healthcare system ranking 8 in the world. The reason that brought me to such an unusual destination was the Buck Advisory Council Meeting. I learned a lot there, but I would like to draw your attention to the topic of one of the three major neurodegenerative diseases – Huntington’s disease.
The Longevity Party - started by IEET contributors Ilia Stambler and Maria Konovalenko - already has chapters in 18 nations, after only two months of existence: Russia, the US, Israel, Finland, Georgia, Canada, Italy, Norway, Denmark, Netherlands, Belgium, Ireland, Mexico, Uganda, South Africa, Korea, Philippines, Singapore.
In a recent Huffington Post article, author George Young asks if we really want to be immortal. He tells the readers about Igor Vishev, a Russian philosopher, who believes that the first people to become immortal are likely to be already born today.
Dr. Jonathan M Rothberg of Life Technologies is the first researcher to officially register for participation in the Archon Genomics Prize, an award given by the X Prize Foundation for the first man to sequence 100 whole genomes of centenarians in less than 30 day for $1,000 or less.
On July 19, we made the first step towards the creation of the Longevity Party. The initiative group of 10 people gathered together in Moscow to establish the first political party aimed at extending human lifespan using technological advances.
A report on a talk delivered by Dale Bredesen at the the Buck Advisory Council meeting at the Buck Institute for Research on Aging in Novato, California. Dale Bresdesen is a specialist in neurodegeneration and Alzheimer’s disease.
Naked mole rats basically live 9 times more than “they should.” At an age equivalent to a human age of 92 years, naked mole-rats show unchanged levels of activity and metabolic rate, as well as sustained muscle mass, fat mass, bone density, cardiac health, and neuron number.
I read this recent opinion in the New York Times, entitled “Age and Its Awful Discontents” by Louis Begley, and it resonated with my personal feelings about the topic. The author vividly describes the last years of his mother’s life, who had been a widow for the previous 40 years before her death.
Aging biomarkers are parameters that always, and in all people, change during aging. It is possible to evaluate and improve therapies that are aimed at slowing down aging, using the biomarkers of aging.