Position Paper: The Critical Need to Promote Research of Aging Below is the position paper on the Critical Need to Promote Research of Aging of the International Society on Aging and Disease (ISOAD). This paper briefly details the rationales, the technologies and the policies that are needed to promote this research. Thus it can serve as a generally applicable advocacy or lobbying paper in different countries. Please help spread it. Please contribute to the widest possible recognition and support of biological research of aging and aging-related diseases. We welcome the readers to circulate this position paper, share it in your social networks, forward it to politicians, potential donors and media, organize discussion groups to debate the topics raised (that may later grow into grassroots longevity research and activism groups in different countries), translate this position paper into your language, reference and link to it, even republish it in part or in full (for example, the policy recommendations can fit on a single page flyer), join the ISOAD or other aging and longevity research and advocacy organizations.
Opposition to IUD’s, like opposition to vaccines, is putting American families at risk—and a Colorado controversy shows that misguided faith and scientific ignorance are to blame. When a pilot program in Colorado offered teens state-of-the-art long acting contraceptives—IUD’s and implants—teen births plummeted by 40%, along with a drop in abortions. The program saved the state 42.5 million dollars in a single year, over five times what it cost. But rather than extending or expanding the program, some Colorado Republicans are trying to kill it—even if this stacks the odds against Colorado families.
Yesterday, I posted a piece examining the oft-quoted mortality rate for measles of one to two deaths per thousand cases of infection. Today, I want to look at what can be learned from more recent and more comprehensive dataset – this one from the 2008-2011 measles outbreak in France.
Back in 1973, Bernard Williams published an article about the desirability of immortality. The article was entitled “The Makropulos Case: Reflections on the Tedium of Immortality”. The article used the story of Elina Makropulos — from Janacek’s opera The Makropulos Affair — to argue that immortality would not be desirable. According to the story, Elina Makropulos is given the elixir of life by her father. The elixir allows Elina to live for three hundred years at her current biological age. After this period has elapsed, she has to choose whether to take the elixir again and live for another three hundred. She takes it once, lives her three hundred years, and then chooses to die rather than live another three hundred. Why? Because she has become bored with her existence.
A woman who values fertilized eggs or who believes her deity does should use the most highly effective contraceptive available. Most fertilized eggs spontaneously abort during the first weeks of life. Estimates of death before implantation range as high as 80 percent and bottom out around 45.
I’ve met Erik Parens twice; he seems like a thoroughly nice fellow. I say this because I’ve just been reading his latest book Shaping Our Selves: On Technology, Flourishing and a Habit of Thinking, and it is noticeable how much of his personality shines through in the book. Indeed, the book opens with a revealing memoir of Parens’s personal life and experiences in bioethics, specifically in the enhancement debate. What’s more, Parens’s frustrations with the limiting and binary nature of much philosophical debate is apparent throughout his book.
A 17-year-old girl, listed in court papers only as Cassandra C., is in protective custody at a Connecticut hospital where she is being forced to undergo chemotherapy treatment that she says she does not want. Americans strongly value the right to refuse medical care.
Anti-aging guru Aubrey de Grey's prediction that the first person to live 1,000-years has already been born got me thinking. What might life be like in this long-range future? Will boredom set in as we count the centuries; or will what promises to be an incredible technology-rich life keep the excitement alive?
There’s a pervasive notion that monogamous relationships are the end-all-be-all – the default pact in human couplings that keep the fabric of society from being torn apart. But growing numbers of scientists believe monogamy is not our biological default; and may not even represent the best road to happiness.
Every human being has both a minimum and a maximum amount of life hours left to live. If you add together the possible maximum life hours of every living person on the planet, you arrive at a special number: the optimum amount of time for our species to evolve, find happiness, and become the most that it can be. Many reasonable people feel we should attempt to achieve this maximum number of life hours for humankind. After all, very few people actually wish to prematurely die or wish for their fellow humans’ premature deaths.
The Immortalists is a film following the lives of two scientists, Aubrey De Grey and Bill Andrews, on their scientific quest to end aging. With the visionary goals set out by the two scientists, they are accompanied by directors Jason Sussberg and David Alvarado who masterfully unveil layers of sensitive philosophical issues surrounding death, existentialism, and our global focuses as a species. The film is a must see for those inclined to explore how these themes tie into aging. Below is an interview with David that covers some film specific questions, with an emphasis on the broader scope of some Transhumanist aims.
When you have to make hard medical decisions, who do you want in the room? Religious belief is on the decline in the U.S., and medical knowledge is on the increase. This makes it particularly ironic that so much of our health care system is accountable at the highest levels not to science or patient preference but to the dictators of faith and of theology. Metaphorically, more and more medical decisions get made with the Catholic Bishops in the room, regardless of whether the patient wants them there. Not only that, but the Bishops have a religious veto that can trump both doctor and patient.
Anti-aging activist Aubrey de Grey has identified medical advances that will eliminate much of the wear and tear our bodies suffer as we grow old. Those who undergo continuous repair treatments, de Grey said in this YouTube interview, could remain healthy for millennia without fears of dying from old age.
Positive future watchers believe we will see more progress in the next three decades than was experienced over the last 200 years. In The Singularity is Near, author Ray Kurzweil reveals how science will change the ways we live, work, and play. The following timeline looks at some amazing possibilities as we venture ahead in what promises to become an incredible future…
Whether you consider yourself a futurist, a technoprogressive, a Transhumanist, we all recognize the ongoing neglect by mainstream media, Hollywood, and other prominent media institutions in regards to a growing realization – the concepts of both work and death are changing before our very eyes! From technological unemployment now starting to affect workers in the industrial nations, to the international scientific community becoming more involved in anti-aging research, it’s quite clear that our near future may see the destruction of what we consider “working” and “dying.”
So I have another paper coming out. It’s about plea-bargaining, brain-based lie detection and the innocence problem. I wasn’t going to write about it on the blog, but then somebody sent me a link to a recent article by Jed Radoff entitled “Why Innocent People Plead Guilty”. Radoff’s article is an indictment of the plea-bargaining system currently in operation in the US. Since my article touches upon same thing, I thought it might be worth offering a summary of its core argument.
Imagine a bracelet or watch that changes into something else when you take it off. Perhaps it becomes a cell phone, tablet, or computer. Although this scenario may seem like science fiction, this and much more will soon become reality with a ground-breaking new technology known as claytronics.
“I think it very likely—in fact, inevitable—that biological intelligence is only a transitoryphenomenon… If we ever encounter extraterrestrial intelligence, I believe it is very likely to be postbiological in nature …” Paul Davies
Looking back on my early experience as a young engineer, I am reminded how little my colleagues and I appreciated that what we did would change the world, for good and for bad. I am also reminded how Marcel Golay, one of my early mentors understood the duality of technology and how this feature plays large in its application for the right purpose.
Samuel Scheffler made quite a splash last year with his book Death and the Afterlife. It received impressive recommendations and reviews from numerous commentators, and was featured in a variety of popular outlets, including the Boston Review and the New York Review of Books. I’m a bit late to the party, having only got around to reading it in the past week, but I think I can see what all the fuss was about.
I recently published an unusual article. At least, I think it is unusual. It imagines a future in which sophisticated sex robots are used to replicate acts of rape and child sexual abuse, and then asks whether such acts should be criminalised. In the article, I try to provide a framework for evaluating the issue, but I do so in what I think is a provocative fashion. I present an argument for thinking that such acts should be criminalised, even if they have no extrinsically harmful effects on others. I know the argument is going to be unpalatable to some, and I myself balk at its seemingly anti-liberal/anti-libertarian dimensions, but I thought it was sufficiently interesting to be worth spelling out in some detail. Hence why I wrote the article.
We women hear a lot about side effects of birth control, but we don’t hear as much about the side benefits. If you haven’t had a conversation with your doctor lately about family planning, you may be in for some surprises, like the fact that lighter, less frequent periods may be healthier for you.
In Human Purpose and Transhuman Potential: A Cosmic Vision for Our Future Evolution, IEET affiliate scholar Ted Chu, a professor of Economics at New York University in Abu Dhabi and former chief economist for General Motors and the Abu Dhabi Investment Authority, argues that post-humanity is a logical and necessary evolutionary next step for humanity, and we need a new, heroic cosmic faith for the post-human era. “The ultimate meaning of our lives rests not in our personal happiness but in our contribution to cosmic evolution,” says Chu…
Summary of Michio Kaku’s Visions: How Science Will Revolutionize the 21st Century (1997) “There are three great themes in science in the 20th century—the atom, the computer, and the gene.” – Harold Varmus, NIH Director. Three centuries ago Newton said that he was a boy, playing on the seashore while a “great ocean of truth lay all undiscovered before me.” Life in Newton’s time was, as Hobbes said, “nasty, brutish, and short.” But Newton unleashed a revolution that he could never have imagined. Within a few generations “the basic laws of matter, life, and computation were … solved.” [3-4]
Accumulating evidence suggests that microbiota plays an important role in modulating lifespan. This makes possible to use symbiotic bacteria as “living drugs”, which live in the host organism and promote its longevity. We propose to create bacteria, which dramatically extend lifespan of its host. Such bacteria have to produce not one, but a set of longevity-promoting substances with optimal concentrations and dynamics of secretion. To obtain such bacteria we propose to use directed evolution, a process that mimics Darwinian selection on a laboratory scale.
I argued in my 2013 book, The Infinite Resource, that the “seeds shouldn’t be patented” argument against GMOs and specifically against Monsanto was invalid for a very specific reason: Patents end. As I wrote then, the patents for Monsanto’s first commercial genetically modified crop, Roundup Ready Soy I, would expire at the end of the 2014 growing season. After that, farmers would be free to save seeds to replant, universities would be free to tinker with the genetic trait, seed breeders would be free to cross-breed it into other strains, and so on.
“Nobody would try ECT (for fun),” says Lesley Galasso, who administers the Brainsway device to treat stubborn clinical depression. “Yet we all tried this (at a low frequency) when we had our training…”
My son recently shared an interesting idea. Suppose we cryogenically preserve ourselves and send our bodies and brains into space, or simply leave them on earth to be reanimated. Even if advanced beings find us in the future and want to awaken us, there is a good chance that our minds will be too primitive to be rebooted. Our futuristic descendants may not have technology compatible with our primitive mind files. It would be as if we come across an old floppy disk or early telephone but no longer had the technology to run them.
If predictions by future thinkers such as Aubrey de Grey, Robert Freitas, and Ray Kurzweil ring true – that future science will one day eliminate the disease of aging – then it makes sense to consider the repercussions a non-aging society might place on our world.
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