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MULTIMEDIA: Maria Konovalenko Topics The dilemma of human enhancement
Longevity Cook Book
Open Source Biotech: Fund Anti-Cancer Research and Make Drugs Cheaper at the Same Time
Achieving Personal Immortality Roadmap
Recent News on Longevity and Health
Can We Live Forever – a Cool Video From the Advanced Apes
Roadmap to Immortality – Artificial Intelligence
Roadmap to Immortality – Nanomedicine
Roadmap to Immortality – Cyborgization, and Cryonics
Craig Venter Decided to Beat Calico in the Race towards Human Life Extension
Projects to accelerate radical healthy longevity
Robert Shmookler Reis on Fighting Aging Approaches and Role of Basic Science
Dark Matter of Transhumanism
Second Transhumanist Political Meeting in Moscow


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Maria Konovalenko Topics
Vision > Bioculture > Contributors > Maria Konovalenko > HealthLongevity
Maria Konovalenko
Longevity Cookbook: Pharmacological Extension of Lifespan by Maria Konovalenko

Here is a teaser from the Longevity Cookbook project.

The first chapter is on pharmacologic enhancement of lifespan. This chapter includes different ways of trying to develop pharmaceuticals to combat aging.

Contributors > Maria Konovalenko > HealthLongevity > Enablement > Innovation
Maria Konovalenko
Genome Stability Leads to Negligible Senescence by Maria Konovalenko

What would you say if I told you that aging happens not because of accumulation of stresses, but rather because of the intrinsic properties of the gene network of the organism? I’m guessing you’d be like: o_0.

So, here’s the deal. My biohacker friends led by Peter Fedichev  and Sergey Filonov in collaboration with my old friend and the longevity record holder Robert Shmookler Reis published a very cool paper.

Contributors > Maria Konovalenko > HealthLongevity > Enablement > Innovation
Maria Konovalenko
A Possible Way to Cure Baldness by Maria Konovalenko

There is something important going on in the fight against baldness.

As in the majority of tissues, the hair follicle has stem cells. There are two types of stem cells that are responsible for the continuous renewal of the follicles. The first type is called active stem cells and they start dividing quite easily. Stem cells of the second type are called quiescent and in case of the new hair growth they don’t start dividing as easily. At the same time, the new hair is based primarily on quiescent cells, which attracted close attenti...

Vision > Contributors > Maria Konovalenko > HealthLongevity > Enablement > Technoprogressivism
Maria Konovalenko
The mTOR Story Part 1 – What Makes This Important Pro-Aging Molecule Active? by Maria Konovalenko

I have mentioned mTOR as one of the main aging genes on multiple occasions. It’s about time I tell you what it is, what it does and why it is so important in aging.

mTOR has a little m in front of TOR, which means I am speaking about mammals. It technically means «mechanistic» TOR, but think of it as the molecule that mice and all of us have, whereas in worms is it just TOR.

Rights > HealthLongevity > Vision > Contributors > Maria Konovalenko > Enablement > Technoprogressivism > ReproRights
Maria Konovalenko
It is Unethical Not to Use Genetic Engineering by Maria Konovalenko

When I hear that the conversation is about an ethical problem I anticipate that right now the people are going to put everything upside down and end with common sense. Appealing to ethics has always been the weapon of conservatism, the last resort of imbecility.

Contributors > Maria Konovalenko > HealthLongevity
Maria Konovalenko
Fighting Death with “The Longevity Cookbook” by Maria Konovalenko

The most significant event in a person’s life is death. It changes everything. More precisely, it takes everything that a person had. If he was in love, he no longer is. If he was aspiring to pleasures, there will be none any longer. The world will be gone for the person.

Every single neuron will disappear that was responsible for the wishes, desires, and feelings. We don’t realize this, but everything single thing we accomplish, we do so looking in the face of inevitable death. Death takes away the sense of a person’s life....

Rights > HealthLongevity > GlobalDemocracySecurity > Vision > Contributors > Maria Konovalenko > Technoprogressivism
Maria Konovalenko
Transhumanism Strategy Boils Down to Choosing a Crowdfunding Project by Maria Konovalenko

First of all, let’s draw a line between a strategy and wishful thinking. There are plenty of wonderful transhumanist projects. A viral video, a global portal, attracting celebrities, proof that aging is a disease, convincing billionaires, educational programs, letters to politicians, civil actions, participating in elections, creating a strong community, clinical trials of combinations of existing age delaying drugs on animals, TV shows, Hollywood blockbusters, creating a political committee, conferences on transhumanist topics, scient...

Rights > HealthLongevity > GlobalDemocracySecurity > Vision > Contributors > Maria Konovalenko > Sociology
Maria Konovalenko
Transhumanism Strategy by Maria Konovalenko

We’ve put together the survey on transhumanism strategy to reveal the inner discussion inside the transhumanist movement. Our goal is to inspire the people to act. We believe the greatest sin in our field is wishful thinking. It’s when a person is saying that it would be good to do something, like for instance, to shoot a viral video, but at the same time this person is not doing anything. His or hers advice has to be implemented in real life somehow on its own.

Rights > HealthLongevity > GlobalDemocracySecurity > Vision > Bioculture > Contributors > Maria Konovalenko > Innovation
Maria Konovalenko
Cure for Aging Can Be Created Using Directed Evolution by Maria Konovalenko

Accumulating evidence suggests that microbiota plays an important role in modulating lifespan. This makes possible to use symbiotic bacteria as “living drugs”, which live in the host organism and promote its longevity. We propose to create bacteria, which dramatically extend lifespan of its host. Such bacteria have to produce not one, but a set of longevity-promoting substances with optimal concentrations and dynamics of secretion. To obtain such bacteria we propose to use directed evolution, a process that mimics Darwinian selec...

Rights > HealthLongevity > GlobalDemocracySecurity > Vision > Bioculture > Contributors > Maria Konovalenko > Innovation > Disability
Maria Konovalenko
Longevity Gene Therapy – Updated Projects by Maria Konovalenko

While discussing the longevity gene therapy project we encountered various questions and observations that prompted us to broaden the project and slightly change it. Generally, all the comments can be reduced into 5 main points…