By explicating the general approach underlying 'gradual mind uploading', transplantology, prosthesis, cell replacement therapy, whole-body induced somatic cell turnover, tissue engineering, gene therapies and chromosome replacement therapies, he draws methodological continuity between its variations and articulates a methodological and taxonomic system for distinguishing between them. Ultimately, Franco argues that the indefinite perpetuation of the CNS via is possible through the gradual and recurrent functional restoration of its constituent integral-components.

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