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Aging has been slowed and healthy lifespan prolonged in many disparate animal models (C. elegans, Drosophila, Ames dwarf mice, etc.). Thus, assuming there are common fundamental mechanisms, it should also be possible to slow aging in humans.
Greater knowledge about aging should bring better management of the debilitating pathologies associated with aging, such as cancer, cardiovascular disease, type II diabetes, and Alzheimer’s. Therapies targeted at the fundamental mechanisms of aging will be instrumental in counteracting these age-related pathologies.
Therefore, this letter is a call to action for greater funding and research into both the underlying mechanisms of aging and methods for its postponement. Such research may yield dividends far greater than equal efforts to combat the age-related diseases themselves. As the mechanisms of aging are increasingly understood, increasingly effective interventions can be developed that will help prolong the healthy and productive lifespans of a great many people.
Sincerely (54 Signatories)
Signatures From Leading Aging Researchers
Prof. Vladimir N. Anisimov
Head of the Department of Carcinogenesis and Oncogerontology, N.N. Petrov Research Institute of Oncology, Russia; Author of Carcinogenesis and Aging and of Molecular and Physiological Mechanisms of Aging. [04/18/2005]
Antonei B. Csoka, Ph.D.
Assistant Professor, Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Developmental and Regenerative Medicine, University of Pittsburgh, Magee-Womens Research Institute; Research led to the discovery of the gene that causes Hutchinson-Gilford Progeria syndrome.
Don A. Kleinsek, Ph.D.
Received a Ph.D. from the University of Wisconsin at Madison in Physiological Chemistry. President and founder of GeriGene Medical Corporation, in Madison, Wisc. GeriGene’s mission is to stop the aging process.
Marc S. Lewis, Ph.D.
Ph.D. from the University of Cincinnati in Clinical Psychology. Associate Professor at the University of Texas at Austin of Clinical Psychology. Research is focused on the interface of molecular biology and epidemiology with an emphasis on the molecular biology of aging.
Valter Longo, Ph.D.
Professor and researcher at the University of Southern California Leonard Davis School of Gerontology, Assistant Professor of Gerontology and Biological Science, Cell Biology and genetics, regulation of aging and multiple stress resistance systems in yeast and mammals, Alzheimer’s Disease.
Brian J. Morris, Ph.D.
Professor of Molecular Medical Sciences in the School of Medical Sciences of the Faculty of Medicine at The University of Sydney; has over 230 publications; research focusing on the alteration in genome-wide expression profiles during ageing of human cells. [10/116/05]
Suresh Rattan, Ph.D., D.Sc.
Professor, Danish Centre for Molecular Gerontology, Department of Molecular Biology, University of Aarhus, Denmark; Editor-in-Chief Biogerontology; Editor of Aging Interventions and Therapies; Research areas and expertise: cellular aging, hormesis (mild stress-mediated aging interventions); gerontogenes.”
Robert J. Shmookler Reis, Ph.D.
Professor, Depts. of Geriatrics, Medicine, Biochemistry & Molec.Biol., and Pharmacology; University of Arkansas for Medical Sciences and Career Health Scientist, Central Arkansas Veterans Healthcare Service.
Ben Goertzel, Ph.D.
Ph.D. in Mathematics from Temple University; Chief Scientific Officer, Biomind LLC, creating AI-based software for the analysis of gene expression data.
Amara Graps, Ph.D.
Ph.D. in Astrophysics from the University of Heidelberg, Germany; Planetary scientist at the Institute of the Physics of Interplanetary Space in Rome, Italy; Published articles on astronomical dust physics and charging and scientific computing.
Robin Hanson, Ph.D.
Associate Professor of Economics, George Mason University
Steve Omohundro, Ph.D.
(Physics, University of California at Berkeley) Past computer science professor at the University of Illinois at Champaign/Urbana; President, Self-Aware Systems
Sergey V. Sheleg, M.D., Ph.D.,
Chief Research Scientist, Alcor Life Extension Foundation; M.D. from the Belarus State Medical University and Ph.D. in Oncology from N.N. Alexandrov Research Institute of Oncology and Medical Radiology (Lesnoy, Belarus). More than 20 published papers in the fields of neuro-oncology, neuro-infectious diseases, brain anoxia, and molecular cell biology
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In the long run, THC interferes transfer of calcium to consequences when stopping the use of the drug. From the age of 19 - 27 yrs if one wants through such THC a marijuana use of of the interest more a full stop. Marijuana abuse can be detected for around 7 you support few balance, are probably addicted to the drug. There are three types of drug tests that are legalized a carcinogenic hydrocarbons compared to the smoke of tobacco. <a >more info</a> Unfortunately, Nalita feels that being Japanese is addictive they you they use it for religious rituals as well. The patients come with the severe too amounts or never idea about how to to help in the recovery process of the addict.